//m.lakotalakes.com/jcicm Heighpubs开放获金博宝app体育取期刊上 en - us 08/17/2021//m.lakotalakes.com/jcicm/jcicm-aid1036.php & lt; h2> Abstract< / h2>& lt; p>背景:新严重急性呼吸系统综合症冠状病毒2 (SARS-CoV-2)爆发严重影响了法国东北部从2020年3月至5月。大规模到来SARS-CoV-2阳性患者在重症监护病房(ICU)提出的问题如何影响免疫功能低下的患者。因此,我们分析了临床、生物和辐射特性的24免疫功能不全的ICU患者严重SAR-CoV-2感染。;/ p>& lt; p>结果:死亡率明显高于免疫功能不全的患者与其他患者相比(分别为41.7%和27.3%,p = 0.021)。死亡率发生在前两周的精心护理之后,突显出可能的兴趣长期完整代码managnement这些病人。最后,淋巴恶性血液病患者似乎特别的影响,大多与单克隆gamma-pathology。; / p>& lt; p>结论:SARS-CoV-2急性呼吸道综合征在免疫力低下的病人的死亡率很高。没有治疗与生存相关的改进。长时间的完整代码管理这些病人。你们需要;/ p> 08/23/2021//m.lakotalakes.com/jcicm/jcicm-aid1037.php & lt; h2> Abstract< / h2>& lt; p>评估操作环境的微生物负载在日常前,内部,和手术后的程序在一个军事应急医院的外科在布加勒斯特显示术中细菌污染的空气通过增加细菌的数量超过允许的最大水平和应变的检测大肠杆菌(大肠杆菌)。;/ p> 08/10/2021//m.lakotalakes.com/jcicm/jcicm-aid1035.php & lt; h2> Abstract< / h2><p>Background: Delirium is an acute syndrome of organ dysfunction with long-term consequences which commonly occurs in the Intensive Care Unit (ICU). The incidence of delirium ranges from 30% - 50% in low severity ICU patients and up to 80% in mechanically ventilated patients. This condition is frequently under-recognized and daily routine screening is a key strategy to early intervention. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) and the Intensive Care Delirium Screening Checklist (ICDSC) are the most recommended assessment tools for detecting delirium in the critical ill patient.</p> <p>Objective: The main objective of this study is to educate ICU staff about delirium. In addition, nurses were trained to use the CAM-ICU as a standard screening tool. The intervention was evaluated through a survey aimed at ICU staff.</p> <p>Methods: An educational intervention was started in 2014 in our ICU. An educational package for ICU staff consisted of a didactic brochure and explanatory videos. One-on-one teaching, case based scenarios and didactic teaching were strategies used in the implementation process. The entire intervention was evaluated by means of a survey directed to the professionals.</p> <p>Results: The structure of the didactic brochure was simple in order to have an easy understanding of the CAM-ICU tool. We also created 10-minute videos. According to the results of the satisfaction survey (N=62), disorganized thinking was the most difficult feature of CAM-ICU to interpret. When in doubt, consultation between co-workers was the primary resource selected by unit staff.</p> <p>Conclusion: This initiative achieved the objective of training health care professionals in the application of the CAM-ICU tool with a good level of satisfaction from them. Therefore, ICU staff consider delirium management in the broader picture of critically ill patient care as a major activity of daily practice.</p> 07/27/2021//m.lakotalakes.com/jcicm/jcicm-aid1034.php & lt; h2> Abstract< / h2>& lt; p>对数以百万计的患者出现慢性疼痛尽管药物治疗,脑深部电刺激(DBS)提供了一个希望的灯塔。在过去十年中该领域已经从星展银行转向其他形式的神经调节,尤其是脊髓刺激(SCS)。DBS疼痛仍在执行,尽管在美国和英国的标示外,和经验变量成功率。你们;/ p>& lt; p> SCS是一个极其有用的工具为疼痛的调制,但有限的应用程序特定目的:疼痛。我们提倡使用DBS疼痛,对病人来说,药理学未能和为谁脊髓刺激是不够的。DBS对慢性疼痛是过早忽视的风险。这里我们大纲这如何发生,在这个过程中,认为这个过程。你们尚未开发的潜力;/ p> 04/26/2021//m.lakotalakes.com/jcicm/jcicm-aid1033.php & lt; h2> Abstract< / h2><p>Introduction: The contents of the retropharyngeal space are limited to fat and retropharyngeal nodes. Primary tumors originating from the retropharyngeal space are rare, therefore, the existence of schwannoma in the retropharyngeal space is infrequent.</p> <p>Method: This paper describes a case of a large schwannoma of the retropharyngeal space excised transorally with the use of co2laser. This lesion measured about 6/6 x 3/5.</p> <p>Result: No peri-or post-operative complications were encountered. The procedure allowed quick resumption of an oral diet and a return to normal activity for the patient.</p> <p>Conclusion: This is, to our knowledge, the first report of this technique used in the excision of a large retropharyngeal space schwannoma.</p> 04/13/2021//m.lakotalakes.com/jcicm/jcicm-aid1032.php <p>The onset of the pandemic has caused widespread concern about the rapid spread of the infection and serious concern about the lack of specific treatment for it.</p> 06/04/2020//m.lakotalakes.com/jcicm/jcicm-aid1031.php & lt; h2> Abstract< / h2>& lt; p>在本文中,我们总结,按时间顺序,所有COVID-19预防措施由澳门特别行政区(SAR)政府在2020年第一季度。本文所包含的信息和故事可能是有用的在世界的其他地方COVID-19控制和预防,尤其是城市人口密度与超高。澳门特别行政区四个主要教训是:(1)积极领导和早期预防。(2)严格遵守社区特有的控制。(3)明确公共卫生的优先考虑。(4)计划缓解金融困境在流行后的经济衰退。;/ p> 05/29/2020//m.lakotalakes.com/jcicm/jcicm-aid1030.php & lt; p>左西孟旦钙敏化剂及其变力的影响主要是由于心肌肌钙蛋白C的细纤维和钙。左西孟旦还能抑制磷酸二酯酶III。变力的影响相比,这并不增加钙离子进入细胞,这解释了左西孟旦不恶化心肌舒张功能不全甚至可能改善舒张功能。左西孟旦不会增加心肌氧的使用,增加冠状血管舒张和心肌氧交付。左西孟旦打开钾离子通道,导致平滑肌细胞膜超极化,从而导致血管舒张[1]。左西孟旦也被报道有抗炎[2、3]和antiapoptotic&,影响[2]。;/ p> 05/19/2020//m.lakotalakes.com/jcicm/jcicm-aid1029.php & lt; p> COVID-19全球的出现在一个前所未有的大流行。COVID-19有很大的死亡率,主要来自急性肺损伤。我们回顾了从中国文学和欧洲关于SARS-Cov2的行为和能力坚持细胞壁[1,2]。基于证据的文献描述了三个组件授予进入靶细胞的病毒包括组织蛋白酶B / L(病毒帽蛋白质所需的初始连接到细胞壁),血管紧张素转换酶2和低PH值环境允许病毒的第一连接细胞壁[3]。我们的案例研究的目的是为了防止非典——SARS-Cov2进入靶细胞通过提高航空公司使用碳酸氢钠吸入PH值。碳酸氢钠吸入(4.2%浓度)安全使用在囊性纤维化患者(CF)浓缩黏液状的压紧(3、4)和氯吸入毒性反对低PH值的影响引起的侮辱代理(4、5)。尚未接种COVID -19名患者尤其是此前研究。;/ p> 03/12/2020//m.lakotalakes.com/jcicm/jcicm-aid1027.php & lt; h2> Abstract< / h2>& lt; p> & lt; strong>背景:& lt; / strong>婚前性实践显著属性增加adolescent&,意外怀孕的风险,早婚,堕胎和性传播感染。在埃塞俄比亚的青少年是为了吸引在早期开始性交没有适当的保护一直是一个问题。研究旨在评估婚前性实践和相关因素的流行在高中学生灵活;/ p>& lt; p> & lt; strong>方法:& lt; / strong>基于设备的研究设计采用。数据收集从291年随机选择Negade和Finca《高中生使用结构化问卷从6月行,2018。Bi-variate逻辑回归用于识别变量,粗暴地用p -值和变量相关,lt;= 0.05安装到多个逻辑回归。 Odds ratio with 95% confidence interval was estimated using multivariable logistic regression to identify independent predictors of premarital sex.</p> <p><strong>Result:</strong> Among high school students, 31.2% reported had experienced premarital sexual practices. This shows that premarital sexual practices among high school adolescent&rsquo;s students were high. Drinking alcohol [AOR = 4.06, 95%CI, (2.06 - 7.99)]. Watching pornographic video [AOR: 2.78, 95%CI, (1.45 - 5.3)] and educational status of mothers [AOR: 0.33; 95% CI (0.13, -0.84)] were significantly associated factors.</p> <p><strong>Conclusion:</strong> Drinking alcohol, watching pornography and mother education were predominantly significantly associated. Therefore, an integrated effort needs to be highlighted to deter the health behavioral problems of school adolescents at the early stages.</p> 12/12/2019//m.lakotalakes.com/jcicm/jcicm-aid1026.php & lt; h2> Abstract< / h2><p>Septic Iliac vein thrombophlebitis with associated psoas abscess is a rare and severe entity, which diagnosis is challenging when no risk factor is clearly present. We are presenting a case of severe septic cavitary pulmonary emboli complicated with Acute Respiratory Distress Syndrome (ARDS) that evolved rapidly to respiratory distress and multi organ failure.<br /> A 61-year-old Hispanic male, had multiple emergency department visits due to back pain, being most of them intramuscular pain medications and steroids. In the history, he had back pain that worsened accompanied by poor mobility, generalized malaise, fever and chills. Computed tomography (CT) scan showed a paravertebral psoas abscess with L5 - S1 diskitis/spondylitis inflammatory changes, which was then later evidenced by a gallium study. Further imaging studies were done, showed bilateral cavitary lung lesions, consistent with septic emboli. Subsequent blood cultures were positive for Methicillin Resistant Staphylococcus Aureus (MRSA), for which a successful combined therapeutic regimen was used. Transthoracic and transesophageal echocardiogram were not suggestive of endocarditis. Staphylococcus aureus (SA) bacteremia is one of the most common serious bacterial infections with a high risk of metastatic complications, which makes this pathogen a unique one. The combination of factors iliac vein thrombophlebitis, psoas muscle abscess, diskitis/spondylitis with ARDS makes cavitary pulmonary disease a challenging perspective. After a 6-week antimicrobial treatment, full anticoagulation, his clinical condition and image findings improved, and he was recently admitted for physical rehabilitation. Major vessels thrombophlebitis should always be considered, when primary source of septic pulmonary emboli is not clear. This case illustrates the complexity of illness and complications that may arise from a source of infection as the one in this patient. Further therapeutic strategies were tailored accordingly.</p> 12/09/2019//m.lakotalakes.com/jcicm/jcicm-aid1025.php & lt; h2> Introduction< / h2>& lt; p>脑干死亡是当一个人已经永久的失去了潜在的意识和呼吸的能力。,当这一切发生的时候,一台机器称为通风保持氧气流通person&,年代血液——一个人确认死亡时他们的脑干功能永久丢失[1]。;/ p> 08/22/2019//m.lakotalakes.com/jcicm/jcicm-aid1024.php & lt; h2> Introduction< / h2>& lt; p>中风后冠状动脉干预是一种毁灭性的和最可怕的并发症与signi&β;性意义的发病率和死亡率。各种因素已经赋予了这种并发症包括技术错误[1]。一小部分中风是医源性,包括那些与创伤性心脏手术有关。根据文献,这是一个罕见的左心导管术的并发症[2]。经皮冠状动脉介入越来越多用于治疗弥漫性动脉粥样硬化患者,急性冠脉综合征,甚至高危患者射血分数低[1]。作者描述一个病人接受经皮冠状动脉介入下梗死的背景下,由缺血性中风在复杂cardic导管插入术。;/ p> 07/22/2019//m.lakotalakes.com/jcicm/jcicm-aid1023.php & lt; h2> Abstract< / h2>& lt; p>酒精滥用是一个全球性的健康问题。酒精戒断综合征(AWS)范围从轻微到严重的症状可导致致命性震颤性谵妄要求入住ICU和导致高医疗成本高达20000美元一个月。最新发表的报告表明,苯巴比妥是一种很有前途的治疗选择AWS管理就是明证ICU招生少,住院的长度,使用辅助药物,医疗费用和关注患者的护理人员比常用的苯二氮平类药物如氯羟去甲安定,安定、利眠宁。苯巴比妥治疗AWS有利,在紧急和住院设置和作为单一疗法或与苯二氮卓类。它是安全的没有严重肝损伤患者,有更好的比苯二氮平类药物的作用机制和更长的半衰期,并导致更少的谵妄和风潮。需要驱动的随机对照试验和庞大的人口,然而安全可以使用苯巴比妥治疗AWS。你们;/ p> 04/19/2019//m.lakotalakes.com/jcicm/jcicm-aid1021.php & lt; h2>信Editor< / h2>& lt; p>在这封信的标题提出的问题是一个自然结果的研究结果和结论,近年来稳步增长的结果治疗急性肺炎(АÐ)。如果你看看医学近年来在这一领域的出版物,事实证明,进步的一个主要障碍改善治疗这一疾病的结果是缺乏适当的方法来确定病原体。因此,缺乏及时的诊断疾病的病因不包括的信息有针对性的抗生素治疗的可能性。近年来,这种遗憾越来越相关,扮演的是治疗失败的主要解释.Continuing缩小的单向视图问题,只关注微生物因素疾病的主要原因,这种观点实际上是另一个幻觉,这即使是在假设的情况下实现,不会表现出明显的总体趋势的变化。这句话很容易验证,如果你依赖于众所周知的事实,而不是使用作为参数假设和猜测。;/ p> 02/07/2019//m.lakotalakes.com/jcicm/jcicm-aid1020.php & lt; h2> Abstract< / h2>& lt; p>本文提出了x射线解剖研究的结果56整个肺准备,后立即进行尸检的孩子死于АP。在47例进行对比的船只和9例支气管树。结果可以澄清一些细节的病机АP和附加参数支持疾病的新学说。;/ p> 02/04/2019//m.lakotalakes.com/jcicm/jcicm-aid1019.php & lt; h2> Abstract< / h2>& lt; p>现代美联社概念只关注的传染性疾病和某些病原体的存在。这种信念决定了治疗的原则,缺乏有效性仍是卫生专业人员的关注。本文提出了一种片段病因的研究致力于АP。994年4月14岁儿童与各种形式的所谓的检查和治疗社区获得性肺炎。细菌检验的材料从542年的炎症区进行了病人。实验建模АP及其胸膜并发症进行44的动物。结果和批判性分析的文献数据和科学事实让我们只考虑细菌的病因的元素АP,这并不是强制性的在所有情况下的疾病。科学为基础修订现有的关于AP的原因和机制发展导致需要彻底改变治疗的原则,是解决问题的战略方向。;/ p> 01/24/2019//m.lakotalakes.com/jcicm/jcicm-aid1018.php & lt; h2> Abstract< / h2><p><strong>Background</strong>: Skin diseases is a common worldwide problem. It affected every aspect of patients&rsquo; quality of life (QOL) mainly physically, socially and psychologically.</p> <p><strong>Objectives</strong>: to assess the impact of skin disorders on patients&rsquo; quality of life and to identify factors associated with it.</p> <p><strong>Methodology</strong>: This cross-sectional study was conducted in outpatient dermatology clinic of a tertiary hospital in Malaysia. A random sample of 145 patients with acne, psoriasis and atopic dermatitis (AD) were interviewed using DLQI questionnaire during their scheduled follow-up appointments at dermatology clinic.</p> <p><strong>Main outcome measure</strong>: Self-reported patients&rsquo; QOL due to their skin diseases.</p> <p><strong>Results and discussion</strong>: Out of three skin diseases psoriasis patients had the highest prevalence (39.3%) followed by AD (34.5%) and acne (26.2%). Patients&rsquo; QOL was highly influenced by their skin conditions especially on working/schooling domain. Furthermore, several factors were identified, namely age, working environment, concurrent skin diseases, usage of supplement for skin diseases and type of food as aggravating factors&mdash;that may influence patients&rsquo; QOL. QOL among females and younger adults was found to be more significantly influenced as compared to males and elderly. With respect to working environment, those who had both indoor and outdoor working environment showed the highest impact of their skin conditions on their QOL. Single patients were more influenced by their skin conditions when compared to those who are married, however it was not significant.</p> <p><strong>Conclusion</strong>: Our findings revealed skin disease had negatively impacted individual QOL with different level of aspects. Among the three diseases, AD patients had the worst impact on QOL. Significant predictors of QOL did not relate solely to skin diseases but also other factors such as type of food and working environment.</p> 10/31/2018//m.lakotalakes.com/jcicm/jcicm-aid1017.php & lt; h2> Abstract< / h2>& lt; p> & lt; strong> Introduction< / strong>:高血压危象(HC)是公认的血压(BP)控制不足的结果。高血压危象是进一步分为高血压紧急(HT-E)和高血压紧急(HT-U)。; / p>& lt; p> & lt; strong> Method< / strong>:使用横断面医院研究设计,病人被诊断为有HC 2017年1月至10月间连续招募了研究中。第七届全国委员会联合提出的标准是用于HC。你们的定义;/ p>& lt; p> & lt; strong> Result< / strong>: 81(.81%)例新诊断为HC参加这项研究。这些患者、50例(61.7%)患者遇到HT-E标准,而31例(38.3%)患者HT-U。肾功能损害(16%)、中风(30.8%),急性冠脉综合征(13.6%)和心脏衰竭(22.2%)主要与HT-E相关并发症。81个研究对象中,13例(16%)患者死亡。虽然在住宅没有显著差异,吸烟史,糖尿病和历史之间的饮酒组,年龄(P = .o22),男性性别(.046)、高血压(.007)的历史,历史的非政府雇员(.003),可怜的合规(P = .002)和高病死率显著(P = .041)与高血压相关的紧急(HT-E)。; / p> <p><strong>Conclusion</strong>: This study showed that HT-E has high case fatality rate among patients admitted with hypertensive crisis at kassala teaching Hospital. Therefore early detection of hypertension and appropriate management are the main stay for reducing morbidity and mortality among patients with hypertensive crisis.</p> 10/27/2018//m.lakotalakes.com/jcicm/jcicm-aid1016.php <h2>Short Communication</h2> <p>The Ontario government has been battling with the issue of extensive wait times in hospitals for several years. Although there are many complex reasons that stem off of the issues of wait times, such as available in patient beds and bed blockers (patients who stay in the hospitals for long periods of time after sustaining a massive injury), the primary cause is concentrated as a system wide problem in access to care [1]. Through numerous reforming and restructuring plans, the Ontario government devised a Wait Time Strategy plan to monitor, manage and improve access to health care services including surgeries and time spent in the ER. The strategy was also devised to enhance the efficiency and effectiveness of healthcare provision. The information derived from the results of the Ontario Wait Time Strategy (OWTS) was to be made public to citizens and providers to ensure that everyone is well aware of the results. Yet, it is quite difficult to implement such a strategy if the leadership challenges within the hospital are not addressed [2].</p> 10/17/2018//m.lakotalakes.com/jcicm/jcicm-aid1015.php & lt; h2> Abstract< / h2><p>A 64-year-old woman was referred to our hospital due to progressive dypnoea for the past week, combined with fever and type 1 respiratory failure. White blood cell count and procalcitonin level were normal. The Chest X-ray showed bilateral disseminated pulmonary infiltrates. Within the next 24 hours the patient developed a severe ARDS. A first diagnostic work-up for typical and atypical pathogens as well as serological tests for CMV, RSV, HIV and HSV were negative. Analysis of a second bronchoalveolar lavage fluid revealed Pneumocystis jiroveci DNA. The patient was successfully treated with trimethoprim-sulfamethoxazole and off label use with caspofungin. The cause of the infection was a six week treatment with dexamethasone. The patient developed a toxic epidermal necrolysis during further course, but completely recovered.<br /> <br /> Pneumonia with Pneumocystis jirovecii must also be taken into account in non-HIV patients, whenever there are any indications that cellular immunity may be depressed</p> 10/15/2018//m.lakotalakes.com/jcicm/jcicm-aid1014.php & lt; h2> Abstract< / h2>& lt; p>有变化不同肝脏疾病的治疗方案。准确的诊断ensNusinersen治疗是一种新型的治疗1型脊肌萎缩症(SMA);因此,治疗的不良反应,还没有广为人知,。目前的研究是一个病例报告,声明一个nursinersen治疗后低钠血症的发展。自疗法非常新,实践有限,我们希望这一罕见的并发症将有助于科学文献。;/ p> 09/11/2018//m.lakotalakes.com/jcicm/jcicm-aid1013.php & lt; h2> Abstract< / h2><p><strong>Objectives</strong>: There are variations in therapeutic regimens of different liver diseases. The accurate diagnosis ensures prompt recovery from these diseases. The present study aimed to evaluate the underlying causes of unexplained signs and symptoms associated with liver diseases through biopsies.</p> <p><strong>Methods</strong>: A retrospective study was conducted in a public child care specialty of Lahore, Pakistan. The data was collected from medical records of the patients who were index hospitalized with unexplained clinical presentation of liver disease between 1st July, 2017 and 31st December, 2017. Data were analyzed by using Statistical Packages for Social Sciences (IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp.), and Microsoft Excel (MS Office 2010).</p> <p><strong>Results</strong>: Overall, the records of 53 patients were selected for the study. Most of them were 11 to 15 years of age. The patients were presented with unexplained hepatomegaly (60.4%) and jaundice (40.7%) during index hospitalization which made them eligible for liver biopsy (LB). The findings of LB revealed that the underlying causes of liver diseases in most of the cases were metabolic (33.9%) and inflammatory disorders (22.6%). Majority of the patients were &le;4 years of age, however cryptogenic cirrhosis (39.1%) was commonly found in &gt;10 years of age. Although most of the patients were suffering from metabolic disorders (p-value=0.07) and liver cirrhosis (p-value=0.08) but these were not statistically significant.</p> <p><strong>Conclusions</strong>: LB was beneficial in evaluating the etiologies of unexplained signs and symptoms of liver diseases. It was found that glycogen storage diseases and liver cirrhosis were the most common etiologies of liver diseases among pediatric patients. But etiologies like metabolic and inflammatory diseases were insignificantly associated with gender.</p> 03/16/2018//m.lakotalakes.com/jcicm/jcicm-aid1012.php & lt; h2> Introduction< / h2>& lt; p>治疗各种炎症过程,包括急性肺炎(АP),在过去的几十年中是相同的,并不能反映一个特定疾病的细节。这种治疗的基础是,laquo;抗生素alone& raquo;。需要额外的治疗努力实现通过使用通用的治疗技术,无论诊断。这并不考虑重要的本地化炎症不仅决定了它的临床情况,但是,最重要的是,机制的影响身体的其他器官和系统。;/ p>& lt; p>试图治疗不同疾病的帮助下从理论上讲,一个援助计划不能产生预期的结果。这种方法的徒劳的当前动态结果所示。减少抗生素的有效性和新出现的耐药菌株微生物部队的不断发展新的抗菌素。然而,药剂师的成功不能阻止脓性并发症的人数持续增长的АP与最大容量即使在发达国家,提供病人。现有问题的解决方案,是在另一个平面灵活;/ p> 01/23/2018//m.lakotalakes.com/jcicm/jcicm-aid1011.php & lt; h2> Abstract< / h2><p><strong>Background</strong>: Pulmonary fibrosis is a clinical problem with an enigmatic etiology with no effective therapy. Current therapies for lung fibrosis are ineffective for progression of lung fibrosis and preventing respiratory failure.</p> <p><strong>Objectives</strong>: The aim of this study is to explore the expression of Desmin, &alpha;-smooth muscle actin (&alpha;-SMA) and the telomerase subunit: human telomerase reverse transcriptase (h-TERT) in a spectrum of lung tissue samples consist of lung fibrosis, lung cancer, and healthy controls.</p> <p><strong>Materials and Methods</strong>: The expression of Desmin, &alpha;-SMA and hTERT were studied in samples of 15 pulmonary fibrosis samples, 16 samples of lung cancer and 14 healthy controls investigated. We evaluated Desmin, &alpha;-SMA as well as the expression of components of telomerase (TERT), by methods: RNA Extraction and cDNA synthesis, Real-Time quantitative PCR, Immunohistochemistry, all prepared from lung tissue paraffin blocked.</p> <p><strong>Results</strong>: &alpha;-SMA marker detected 1(8.3%) of healthy control and 11(91.7%) of lung fibrosis samples. The difference between groups was significant (p&lt;0.001). Also the difference between healthy control 1(6.7%) and lung cancer 14 (93.3%) for &alpha;-SMA marker was a significant (P&lt;0.001). It was a significant difference between healthy control and lung cancer for TERT expression (P=.005). TERT was not positive in any sample of neither healthy control nor lung fibrosis. For TERT, it was a significant difference between lung fibrosis and lung cancer by Fisher&rsquo;s Exact Test (P=.004). Expression of TERT and &alpha;-SMA between small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) was not statistically significant (P=.700, P=0758), respectively.</p> <p><strong>Conclusions</strong>: We recommend more investigation to regard &alpha;-SMA, Desmin in patients with lung fibrosis and follow them for possible cancer risk. Also, more study is needed to regard TERT as a marker in lung cancer. Assessment of these markers may have future implication to explain the same way of pathogenesis and carcinogenesis of fibrosis and cancer and for prevention or treatment</p> 11/02/2017//m.lakotalakes.com/jcicm/jcicm-aid1010.php & lt; h2> Abstract< / h2><p>Observing relevant biomedical literature we have see that clinical pharmacist play a crucial role in ICU settings with reducing in mortality rate and improving some clinical outcomes.</p> 09/08/2017//m.lakotalakes.com/jcicm/jcicm-aid1009.php & lt; h2> Summary< / h2>& lt; p>一个原本健康的26岁的绅士,称为从州立医院与所谓的历史从10英尺的高度在一个建筑工地。格拉斯哥昏迷评分(GCS),医院是E2 V2 M5。他带来了我们的应急装置,医院吉隆坡的GCS E1 V2 M4 (7/15)。学生5毫米+ + / 3毫米。他左耳朵流血。否则生命体征稳定,没有其他颅外的损伤。计算机断层扫描(CT)扫描大脑(图1)显示右额颞叶急性硬脑膜下血肿,左frontotemporoparietal急性硬脑膜下血肿,蛛网膜下腔出血与底层,质量效应和中线转向左边超过0.5厘米和基底池。你们的毁灭;/ p> 09/07/2017//m.lakotalakes.com/jcicm/jcicm-aid1008.php & lt; h2> Abstract< / h2>& lt; p>我们报告一例79岁的人呈现给我们的急诊室(ED)晕厥。病人发展严重的心动过缓和低血压。他的心电图对象化缓慢心房纤颤,病人迅速安装昏迷。造影或非脑CT扫描显示双边vertebrobasilar缺血性中风。;/ p> 07/11/2017//m.lakotalakes.com/jcicm/jcicm-aid1007.php <h2>SUMMARY</h2> <p><strong>Objectives</strong>: The study aims to assess the knowledge, attitude and practices of physicians who deal with pediatric age group SSTIs in reference to the Infectious Diseases Society of America (IDSA) guidelines on this regard that was published in 2014.</p> <p><strong>Background</strong>: Skin and soft tissue infections rank among the most frequent infections worldwide.</p> <p>It is estimated that over 11 million ambulatory healthcare visits occur each year in US for skin and soft tissue infections due to Staphylococcus aureus (S. aureus) alone.</p> <p>SSTIs are clinical entities of variable presentation, etiology and severity that involve microbial invasion of the layers of the skin and underlying soft tissues. SSTIs range from mild infections, such as pyoderma, to serious life-threatening infections, such as necrotizing fasciitis. One of the main challenges in managing SSTIs is to be able to identify those who need immediate inpatient intervention versus the more stable ones that can be manages in outpatient basis. In June of 2014, The Infectious Diseases Society of America (IDSA) released evidence based guidelines that has nicely covered all aspects related to the management of SSTIs.</p> <p><strong>Method</strong>:An anonymous 20-item survey exploring knowledge, attitude and practices associated with diagnosis and management of skin and soft tissue infection was distributed to physicians of different levels of expertise (from residents to consultants) in the departments of Pediatrics, Emergency Medicine and Family Medicine in different governmental facilities in Al-Ain city which is one of the major cities in United Arab Emirates.</p> 06/26/2017//m.lakotalakes.com/jcicm/jcicm-aid1006.php & lt; h2> ABSTRACT< / h2>& lt; p>本研究描述了化疗,医疗利用率、总生存期(OS)和无进展生存(PFS)患者被诊断为慢性淋巴白血病(CLL)。新诊断慢性淋巴细胞白血病病人化疗选择从埃因霍温癌症登记在1998 - 2011之间,与患者的立场PHARMO数据库网络包括数据在门诊药品调剂,住院治疗和临床实验室测量。化疗方案的分类使用基于组合。操作系统和PFS后被确定诊断和化疗后。医疗利用率是今年前一年诊断和评估化疗后。;/ p>& lt; p>总共125名慢性淋巴细胞白血病患者接受化疗:化疗52名患者(42%)开始在6个月,73例患者(58%)开始化疗,通用电气,6个月后诊断。意味着(和plusmn; SD)年龄为67岁(及plusmn; 10)年,68%是男性。约50%的两条谱线,约25%有一个治疗的治疗。苯丁酸氮芥是最常见的类型的一线化疗。 Prior diagnosis, 44% were hospitalized for any cause and 94% had at least one drug dispensing. After chemotherapy, this was 43% and 98%, respectively. One-year survival rate after diagnosis was 94%. Median PFS after first treatment line was 17 months for patients starting within 6 months and 27 months for patients starting &ge;6 months after diagnosis. In conclusion, most CLL patients receiving chemotherapy were treated with chlorambucil. One-year after initial diagnosis, 94% were still alive. Median PFS after first line chemotherapy ranged from 17 to 27 months, depending on the timing of chemotherapy.</p> 04/19/2017//m.lakotalakes.com/jcicm/jcicm-aid1005.php & lt; h2> INTRODUCTION< / h2><p>Chest compression is the fundamental technique in cardiopulmonary resuscitation (CPR) in patients with cardiac arrest [1]. The quality and the early implementation of CPR are essential to improve the prognosis and the chances of restoring spontaneous circulation. In the literature, there are some articles about the poor quality of chest compression [2-4]. Therefore chest compression is as crucial as alerting the emergency services or early defibrillation in the survival chain. In accordance with the guidelines, chest compressions have to be performed continuously to improve the outcome [5]. However, the efficacy of manual chest compression diminishes over time with the fatigue of the provider (which appears within minutes of starting the procedure), and is impaired during transportation manoeuvres, which expose patients to unforeseen interruptions and a deterioration in the quality du massage in terms of power and rhythm. The efficacy of manual chest compression has been reported to fall by 20% per minute [6,7]. Mechanical chest compression overcome this problem of operator fatigue by ensuring constant efficacy in terms of both quality and quantity. Even though current data show no difference between manual chest compression and automated systems in terms of survival, haemodynamic studies in animal models have shown that mechanical techniques are more effective [8].</p> <p>The principal aim of this study was to evaluate the hemodynamic impact (systolic, diastolic and mean arterial blood pressure) of the LUCAS&trade; active compression-decompression device (Medtronics&reg; Jolife; Lund, Sweden) as the mechanical chest compression technique versus manual chest compression. The secondary aims were on the one hand to evaluate in a quantitative manner cardiac output and its evolution during mechanical and manual cardiopulmonary resuscitation and on the other hand to evaluate the correlation between cardiac output and other routinely-measured hemodynamic parameters, in particular the EtCO2.</p> 03/14/2017//m.lakotalakes.com/jcicm/jcicm-aid1004.php & lt; h2> ABSTRACT< / h2>& lt; p>癫痫临床表现的突然中断正常皮质神经元的电活动。大脑电活动周期性干扰,改变神经细胞的完整性,增加发射脉冲和扩散到相邻正常神经元与意识的改变导致短暂的大脑功能障碍,行为或运动机能。它可能引发的疾病、感染、压力、中风,脑部肿瘤,或根本原因可能不完全理解。癫痫持续状态(SE)是一个医疗紧急情况,需要及时诊断和治疗。药物治疗包括一般支持措施,抑制癫痫活动和缓解潜在的条件。耐火材料本身需要进入一个重症监护病房(ICU)允许足够的监控和支持呼吸,代谢和血流动力学功能和脑电活动。SE治疗,苯二氮卓类抗癫痫药物的第一行,如果苯二氮平类药物不能控制发作,苯妥英通常是表示;苯巴比妥和卡马西平可能也被考虑。耐火SE、异丙酚、硫喷妥钠代表一线人员经过仔细评估潜在风险。 In refractory SE, general anesthesia may be required. There is currently no unique consensus for definite treatment option of RSE. In this review, the management protocol of seizure, assessment, monitoring, and different alternative therapy would be discussed.</p> 12/30/2016//m.lakotalakes.com/jcicm/jcicm-aid1003.php & lt; h2> ABSTRACT< / h2>& lt; p>甲型肝炎病毒(HAV)感染是急性病毒性肝炎的最常见形式世界各地。复杂的甲型肝炎病例报道发展的演讲。这是一个报告三例non-fulminant甲型肝炎感染注释罕见的非肝sequalae灵活;/ p> 12/22/2016//m.lakotalakes.com/jcicm/jcicm-aid1002.php & lt; h2> ABSTRACT< / h2><p><strong>Background</strong>: Intensive care patients are often in need of sedation to endure being intubated. Light sedation is increasingly common since it has been proved to offer benefits such as faster recovery to patients.</p> <p><strong>Aim</strong>: The aim of this study was to describe critical care nurses&rsquo; experiences of nursing patients lightly sedated with dexmedetomidine.</p> <p><strong>Research Methodology</strong>: Qualitative personal interviews were conducted during 2015 with 10 critical care nurses in Sweden. Interview transcripts were analysed using inductive qualitative thematic analysis.</p> <p><strong>Results</strong>: Light sedation of the patient facilitated communication and interaction with him or her, and the relationship between the patient and his or her family members. Dexmedetomidine was described as a fairly new drug, and the critical care nurses stated that they needed more knowledge about it and about sedation scales in order to learn more about the drug&rsquo;s mechanism of action and its potential side effects on patients.</p> <p><strong>Conclusion</strong>: It is important to critical care nurses to learn more about dexmedetomidine and about sedation scales to assess levels of sedation, as light sedation has been shown to benefit the patient as opposed to deep sedation that can increase recovery time.</p> 12/17/2016//m.lakotalakes.com/jcicm/jcicm-aid1001.php & lt; h2> INTRODUCTION< / h2>& lt; p>非传统的广泛可用性膳食补充剂和药物活性物质通过互联网继续引入机制无意toxidromes不常见。消费者的能力几乎是无限制的获取产品声称增加正常生理的增强的目的,娱乐,和/或潜在的滥用。安全配置文件标准或者有毒剂量在很大程度上仍未知的许多电子代理人可以购买。我们报告一例混合毒性相关phenibut fosaracetam,两者都是现成的消费者从网上零售商购买。书面和口头同意了对于这种情况表现灵活,br /比;,,& lt; / p>