//m.lakotalakes.com/hjc Heighpubs开放获金博宝app体育取期刊上 en - us 04/07/2021//m.lakotalakes.com/hjc/aac-aid1023.php <h2>Abstract</h2> <p>This literature review is concerning with liquid chromatography specifically high performance liquid chromatography (HPLC), Ultra high performance liquid chromatography (UHPLC), chromatography theory, chromatographic parameters, monolithic columns, principles of green chemistry and its application ingreen chromatography.</p> 02/04/2021//m.lakotalakes.com/hjc/aac-aid1022.php <p>In recent years polyolefin nanocomposites are of great interest because of their high potential as materials with novel properties [1,2].</p> 12/02/2020//m.lakotalakes.com/hjc/aac-aid1021.php <h2>Summary</h2> <p>A balance response is the point at which a corrosive and a base respond to shape water and a salt and includes the mix of H+ particles and OH-particles to produce water. The balance of a solid corrosive and solid base has a pH equivalent to 7.</p> 11/26/2019//m.lakotalakes.com/hjc/aac-aid1020.php <h2>Abstract</h2> <p>The incorporation of tellurium into metal carbonyl using tellurium transfer/ extrusion reaction is presented in this work. The results bring one of the new ways to incorporate tellurium by transferring it from one molecule to another molecule, in comparison to the work so far where either insertion or extrusion reactions were shown. The reactions of PhC2TeC2Ph with the metal carbonyl cluster produced thermodynamically stable metal carbonyl tellurium clusters.</p> 07/09/2019//m.lakotalakes.com/hjc/aac-aid1019.php <h2>Introduction</h2> <p>Climate change and the increasing global population pose a severe threat to the availability of freshwater in the world. Over consumption of water and deteriorating water quality are problems that should be addressed in order to ensure water availability for the coming decades. In this context, the increasing presence of micropollutants in water has shown to cause detrimental impact on water quality, given the negative disturbances that they can cause on human health and on the environment. Thus, it is important to study and quantify the presence of micropollutants in water bodies and also in regenerated wastewater based irrigation systems.</p> 06/12/2019//m.lakotalakes.com/hjc/aac-aid1018.php <h2>Introduction</h2> <p>Benzene (B), toluene (T), ethylbenzene (E) and xylene (X), collectively named as BTEX are mono-aromatic ring compounds with a 6-carbon benzene ring. Due to the presence of the aromatic ring, these compounds, especially benzene, are generally considered to be non-reactive species [1]. However, they are known to undergo hydrogenation and certain substitution reaction depending on the prevailing environmental conditions. Their solubility in water is usually low (i.e. relatively hydrophobic in nature) due to the low octanol-water partition coefficient (Kow) values which favour hydrophilic dissolution [2]. BTEX compounds are relatively insoluble in water and in some situations, their levels have been recorded at up to 1000 mg/L, which is much higher than the allowed maximum contaminant level of 0.005 mg/L for B, 1 mg/L for T, 0.7 mg/L for E, and a total of 10 mg/L for all three forms of X [3]. They are released into the natural environment (air, water, soil and sediments) due to landfill leaching, underground storage tanks, accidents during oil transportation and pipeline leakage from petroleum and chemical industries [4].</p> 06/11/2019//m.lakotalakes.com/hjc/aac-aid1017.php <h2>Abstract</h2> <p>This article refers to calculations involved with determination of ethanol, analyzed according to redox back titration principle. A quantitative reasoning, based on logical sequence of statements, is presented for derivation of the formulas required to calculate the results of chemical analyses according to stoichiometric principles. The titrations are considered as two-step analytical procedures. This way, one can gain an insight into a classical redox titration and get a knowledge on the advantages of back titrations.</p> 10/26/2018//m.lakotalakes.com/hjc/aac-aid1016.php <p>Abstract</p> <p>Fluorescein was conjugated with 1-methyl-o-carborane and the resulting bioconjugate was biologically evaluated through microscopic and flow cytometric studies in pancreatic cancer and squamous cell carcinoma cell lines. The uniform distribution of this bioconjugate, as well as its moderate cytotoxicity and higher boron content relative to present boronated delivery agents sodium borocaptate (BSH) and boronophenylalanine (BPA), provide justification for its further evaluation as a potential delivery agent for BNCT.</p> 10/23/2018//m.lakotalakes.com/hjc/aac-aid1015.php <h2>Editorial</h2> <p>When I asked the students in my general Chemistry class whether grade is more important than knowledge, a majority of them opted for grades over knowledge and this answer did not surprise me a bit as the smart phones are available for them to think while their brains are corrupted or unused for most of the time. This brings one to the Einstein&rsquo;s prediction that technology will develop to the point where there is no human interaction, which will be the day a new generation of idiots will emerge, and we are witnessing everywhere, including in the classrooms all over the world.</p> 10/04/2018//m.lakotalakes.com/hjc/aac-aid1014.php <h2>Abstract</h2> <p>The intention of the present work is to validate an easy, better and reasonable approach for estimation of amoxicillin trihydrate in tablet formulation by opposite segment(reverse phase) HPLC &ndash;UV with advanced conditions and parameters for habitual use in Rwanda well known board in pharmaceutical laboratory in order to check if no substandard or counterfeit amoxicillin has entered in our country that can result in antimicrobial resistance, treatment failure which can be a chief difficulty on public health. an easy, selective, precise, speedy, specific, and correct reverse phase HPLC UV-seen technique has been verified for the dedication of amoxicillin, in addition that is a cost-effective technique for the established method, monobasic potassium phosphate (KH2PO4) used as buffer and methanol and had been used as a mobile section in the ratio 95:5 respectively. The elution turned into finished in an isocratic mode at a go with the flow rate of 1.5ml/minute proposed method became demonstrated as according to ICH guiding principle refereeing additionally to USP necessities for amoxicillin capsule. linearity range of amoxicillin and was evaluated inside the variety of 20&ndash;160 g/ml. the correlation coefficient r2 changed into 0.9998 and the relative well known deviation between six replicates injection was always much less than 2%. The retention time was found 3.5&plusmn;0.02. the high percentage of healing of amoxicillin is 100.6&plusmn;4% indicates that the proposed method is exceptionally correct and precise trueness of with the trueness of 100.06&plusmn;1.2% .the statistical evaluation proved that the demonstrated method is appropriate for analysis of amoxicillin as the majority drug and pharmaceutical formula with none interference from excipients .with the aid of considering the efficiency of the drug samples, all analyzed pattern were within the variety of 90-120 % of percentage of labeled amount, but the efficiency had been distinctive amongst samples. The have a look at located that no counterfeit, no substandard product turned into amongst all batches of amoxicillin samples throughout the c programming language of the look at.</p> 09/04/2018//m.lakotalakes.com/hjc/aac-aid1013.php <h2>Abstract</h2> <p>The industrial production and use of chromium have grown considerably during the past five decades. Abundances of the chromium isotopes in terrestrial samples are identical to 0.01%. Among the dominant species of chromium, the trivalent form widely occurs in nature in chromite ores which is extremely immobilized especially in water bodies. Samples were mixtures of separated chromium isotopes and the calibration was made with the same species as those used in the measurements. The method had simplified the conversion of the ores to chromyl fluoride since the element could be readily separated as lead chromate from the leaching of chromite-sodium peroxide fusions. Isotope assay of chromyl fluoride under certain conditions was measured and the measurements of chromium isotopic anomalies ratios and isotope abundance of the chromite ores have been assessed. These provided sufficient quantitative mass spectrometric data, which were analyzed to calculate the abundance and the mean atomic mass of the questioned isotopes. Based on the high mass spectroscopy stability and the correction factors, the results were of good precision (incl. negligible systematic errors normally associated to inter-laboratory discrepancies) and the Cr isotopes availability (52Cr &gt; 53Cr &gt; 50Cr &gt; 54Cr) was in conjunction with other classical tools such as oxygen isotopes. This paper is important for paleoecological, environmental, archeological, forensic, and nuclear researchers.</p> 09/03/2018//m.lakotalakes.com/hjc/aac-aid1012.php <h2>Abstract</h2> <p>Heavy metals and metalloids are dangerous because they have the tendency to bioaccumulate in biological organisms over a period of time. However, it is conceived that a number of phytochemical agents as well microorganism can act as heavy metal removing agent both from human beings and the environment surrounding. For instance, microbes are used for the removal of heavy metals from the water bodies including bacteria, fungi, algae and yeast. This review shows that bacteria can play an important role in understanding the uptake and potential removal behaviour of heavy metal ions. The bacteria are chosen based on their resistance to heavy metals (incl. their toxicities) and capacity of adsorbing them. Due to specific resistance transfer factors, cell impermeability is drastically inhibited by several ion (i.e. mercury, cadmium, cobalt, copper, arsenic) forms. Between these elements, free-ion cadmium and copper concentrations in the biological medium provide more accurate determination of metal concentrations that affect the bacteria, than with most of the other existing media. Metal toxicity is usually assessed by using appropriate metal ion chelators and adjusting pH factor. Bacteria and metals in the ecosystem can form synergistic or antagonistic relationships, supplying each other with nutrients or energy sources, or producing toxins to reduce growth and competition for limiting nutritional elements. Thus, this relation may present a more sustainable approach for the restoration of contaminated sources.</p> 07/13/2018//m.lakotalakes.com/hjc/aac-aid1011.php <h2>Abstract</h2> <p>Like many tropical countries, Sudan has ample biomass resources that can be efficiently exploited in a manner that is both profitable and sustainable. Fuel-wood farming offers cost-effective and environmentally friendly energy solutions for Sudan, with the added benefit of providing sustainable livelihoods in rural areas. This article provides an overview of biomass energy activities and highlights future plans concerning optimum technical and economical utilization of biomass energy available in Sudan. Results suggest that biomass energy technologies must be encouraged, promoted, implemented, and fully demonstrated in Sudan.</p> 04/09/2018//m.lakotalakes.com/hjc/aac-aid1010.php <h2>Abstract</h2> <p>Amyloid-&beta; peptide (A&beta;) and tau protein deposits in the human brain are the pathological hallmarks of Alzheimer&rsquo;s disease (AD). Tau is a class of proteins that are abundant in nerve cells and perform the function of stabilizing microtubules. However, in certain pathological situations, Tau proteins become defective and fail to adequately stabilize microtubules, which can result in the generation of abnormal masses that are toxic to neurons. This process occurs in a number of neurological disorders collectively known as Tauopathies. Tau protein is the major factor of the intracellular filamentous deposits that relate to a number of neurodegenerative diseases which includes the progressive supranuclear palsy (PSP), Pick&rsquo;s disease, and Parkinsonism. The identification of mutations in Tau established that dysfunction or misregulation of tau protein is sufficient to cause dementia and neurodegeneration. In this review article, we discussed the etiology of the tau formation and role in AD and subsequently therapeutic approach for disassembling and Tau inhibition.</p> 11/16/2017//m.lakotalakes.com/hjc/aac-aid1009.php <h2>Abstract</h2> <p>Red blood cell (RBC) alloimmunization can be a life-threatening complication for patients with thalassemia major and sickle cell disease (SCD) who must receive chronic therapeutic transfusions. Chronic transfusions can lead to erythrocyte alloimmunization, patients continue to develop alloantibodies due to the transference of the immunogenic antigens on the donor RBCs. Many complications are possible. Difficulty in finding compatible match units for the patients can cause transfusion delays delayed, or present alternative risks to the patients from delayed hemolytic transfusion reactions. This review discusses the possible mechanisms, risk factors associated with alloimmunization formation and the hemolytic transfusion reactions and also describe the guideline for transfusion management of these patients, including opportunities and emerging approaches for minimizing this life-threatening complication.</p> 10/17/2017//m.lakotalakes.com/hjc/aac-aid1008.php <h2>Abstract</h2> <p>In the current study, combinatorial therapeutic approaches to DNA/RNA of human cancer cells and Benzylpenicillin (Penicillin G), Fluoxetine Hydrochloride (Prozac and Sarafem), Propofol (Diprivan), Acetylsalicylic Acid (ASA) (Aspirin), Naproxen Sodium (Aleve and Naprosyn) and Dextromethamphetamine nanocapsules with surface conjugated DNA/RNA of human cancer cells to targeted Nano drugs for enhanced anti-cancer efficacy and targeted cancer therapy using Nano drugs delivery systems were investigated.</p> 09/26/2017//m.lakotalakes.com/hjc/aac-aid1007.php <h2>Abstract</h2> <p>Pyridine and pyrimidines are amongst the most important, well known heteroaromatic rings, owning to their bioactive importance. Herein, an idea about how to design the synthetic pathway for these rings using retrosynthesis analysis techniques.</p> 09/26/2017//m.lakotalakes.com/hjc/aac-aid1006.php <h2>Abstract</h2> <p>A series of Schiff bases of diphenylamine derivatives have been synthesized and evaluated in vitro for their antibacterial activity against pathogenic both Gram-positive bacteria B. subtilis and Gram-negative bacteria E. coli using ciprofloxacin as standard drug at conc. of 50 &micro;g/ml and 100 &micro;g/ml. The structures of these compounds were established on the basis of IR and 1H-NMR spectral analysis. The compound (3d) displayed potent antibacterial activity against Bacillus subtilis (17 and 15mm) and Escherichia coli (19 and 17mm) by disc diffusion method.</p> 09/22/2017//m.lakotalakes.com/hjc/aac-aid1005.php <h2>Abstract</h2> <p>A study was undertaken during August 2017 to evaluate the effect of salinity on chlorophyll a, chlorophyll b, total chlorophyll, and carotenoid and proline contents of hydroponically grown seedlings of Bruguiera gymnorhizza. The primary aim was to observe its tolerance to changing salinity. The selected seedlings were exposed to five different salinity levels (2,5,10,15 and 20psu) for a period of 30 days and observations were done at a regular interval of 7,14,21 and 30 days respectively. The concentrations of chlorophyll exhibited significant positive correlations with salinity (p&lt;0.01). The chlorophyll a:b ratio in the plant varied between 2.39 to 3.71 throughout the period of investigation. The salinity fluctuation did not affect the carotenoid level and proline content in the leaves of the species as evidenced from the insignificant r values. The results show that Bruguiera gymnorhizza of Indian Sundarbans region can tolerate and adapt to high saline condition as witnessed in the central sector of the deltaic complex around the Matla River.</p> 08/29/2017//m.lakotalakes.com/hjc/aac-aid1004.php <h2>Abstract</h2> <p><strong>Background:</strong> The reaction of 2-(benzo]d[thiazol-2-yl)-3-oxopentanedinitrile 4 with DMF/DMA has been investigated to explore the synthetic potentialities of this novel activated nitrile in heterocyclic synthesis.</p> <p><strong>Results:</strong> Pyrano, pyridino, pyrazolo, azepino and oxothiepano carbonitrile derivatives could be obtained starting from 4 and plausible mechanisms for their formations are reported.</p> <p><strong>Conclusion:</strong> The newly synthesized compounds were assessed for their antimicrobial activity. Compounds 7, 10 and 12 exhibited broad spectrum antibacterial profile against the tested organisms.</p> 06/30/2017//m.lakotalakes.com/hjc/aac-aid1003.php <h2>Abstract</h2> <p>Pine honey represents the major type of honey produced in Greece. In that sense, the aim of the present study was to investigate if specific physicochemical and bioactive properties could serve as markers of its geographical origin. For this purpose, forty pine honey samples were collected during harvesting years 2011 and 2012 from Halkidiki and Thassos, the well-known pine honey producing areas in Greece. Physicochemical parameters taken into account, using conventional and literature cited methods, were: pH, CIE colour parameters<em> L*,a*,b*</em>, and browning index. Furthermore, colour intensity and the in vitro radical scavenging activity were estimated by the application of spectrometric assays. Results showed that, pine honeys exhibited statistically significant differences (p&lt;0.05) in pH, colour intensity, and radical scavenging activity, depending on geographical origin. On the basis of radical scavenging activity results obtained, pine honeys proved to have a high<em> in vitro</em> antioxidant &ldquo;character&rsquo;&rsquo;. Finally, perfect Pearson&rsquo;s correlations (<em>r=1</em>) at the confidence level p&lt;0.01 were obtained for the sets: pH-browning index, pH-radical scavenging activity, and browning index -radical scavenging activity, with respect to geographical origin.</p> 05/24/2017//m.lakotalakes.com/hjc/aac-aid1002.php <h2>Abstract</h2> <p>Mesoporous graphitic carbon nitrides (mpg-CN) were synthesized by a templating method using Ludox (SiO2) as hard template and guanidine hydrochloride (GndCl) as precursor, and were used as metal-free photocatalysts for microcystin-LR (MC-LR) degradation in aqueous solution. By tuning the mass ratio of SiO2 to GndCl, mpg-CN with varied surface areas and condensation degrees were obtained. Catalytic results showed that sample prepared at mass ratio equals 0.4, i.e., mpg-CN(0.4), exhibits the best activity, with above 98% MC-LR conversion obtained at 120 min. Mechanism studies suggested that the reaction obeys the pseudo first-order equation and the produced superoxide anion radicals (&bull;O2&minus;) is the major reactive intermediates contributing to the reaction. Stability tests showed that no appreciable loss of activity is observed even the catalyst is recycled for five times, indicating that the material is stable in the reaction.</p> 02/21/2017//m.lakotalakes.com/hjc/aac-aid1001.php <h2>Abstract</h2> <p>Infectious bursal disease (IBD) considered as one of the major viral diseases threatening the poultry industry worldwide. The causative agent of the IBD is Infectious bursal disease virus (IBDV) which replicates in developing B lymphocytes in the bursa of Fabricius leading to its destruction and bursal inflammation. In this study, we investigated a technology to produce therapeutic recombinant antibodies against IBDV in bacteria by constructing a bacterial displayed recombinant scFv library from immunized chickens, followed by screening the scFv library by fluorescence activated cell sorting (FACS) with FITC-labeled VP2. Twelve VP2-binding scFv clones with unique sequences were obtained, with overall amino acid homology of 81.53%. The complementarity determining region (CDR) 3 in the heavy chain displayed the lowest homology, while the amino acid sequences in framework regions and CDR2 of both chains and CDR1 of the heavy chain are relatively conserved. Twelve VP2-binding scFv clones were expressed in E.coli and purified through denaturation and denaturation of inclusion bodies. Our ELISA results showed that all scFvs exhibited binding ability and specificity to VP2 and various IBDV strains. In addition, two scFvs showed significant neutralizing activity to IBDV (B-87 strain) as these scFvs inhibited cytopathic effect of chicken embryo fibroblast (DF1) caused by IBDV. In conclusion, our study provides a lead candidate for further development of therapeutic antibodies for IBDV infection.</p>