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的oai: heighpubs.org: 10.29328 / journal.ijcar.1001005
2018-01-30
HACR:影响
两种不同剂量右美托咪定对玻璃体视网膜手术单次球周阻滞质量的影响
Nagat年代EL-Shmaa
穆罕默德El-Kashlan
埃曼斋月Salama
& lt; h2> Abstract< / h2>& lt; p> & lt; strong>目的:& lt; / strong>评价在玻璃体视网膜手术中，两种不同剂量的右美托咪定加入局麻药混合物对单次注射球周阻滞质量的影响。& lt; p> & lt; strong>设计:& lt; / strong>一项前瞻性、双盲、随机研究。& lt; p> & lt; strong>设置:& lt; / strong>在我校医院手术室进行。患者:</患者:</该研究包括120例在2016年4月至2017年3月期间进行玻璃体视网膜手术的视网膜疾病患者。& lt; p> & lt; strong>干预措施:& lt; / strong>120例患者随机分为三组，每组40例。 Group I (the control group) received 5-7 ml mixture of lidocaine 2% and Levobupivacaine 0.5% with 120 IU of hyaluronidase, group II received5- 7 ml mixture of lidocaine 2% and Levobupivacaine 0.5% with 120 IU of hyaluronidase +15 µgdexmedetomidine, and group III received5- 7 ml mixture of lidocaine 2% and Levobupivacaine 0.5% with 120 IU of hyaluronidase + 30 µg dexmedetomidine.</p> <p><strong>Measurements:</strong> The primary outcome was to evaluate the impact of adding two different doses of dexmedetomidine on the onset of globe anesthesia and akinesia. Secondary outcomes were the duration of globe anesthesia and akinesia, overall patient satisfaction and surgeon satisfaction.</p> <p><strong>Results:</strong> The onset of globe anesthesia was significantly shorter in group II and III in comparison with group I. Adding dexmedetomidine to the local anesthetic mixture prolonged the duration of globe analgesia, and this difference was statistically significant in group II and III in comparison with the group I.</p> <p><strong>Conclusion:</strong> Adding dexmedetomidine to a mixture of lidocaine 2% and levobupivacaine/hyaluronidase mixture in single injection peribulbar block shortened sensory and motor block onset, extended the analgesia period and the motor block duration with high patient and surgeon satisfaction.</p>
国际临床麻醉与研究杂志-提高科学出版公司188bet体育
2018-01-30
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